A fast, transient K+ current in neurohypophysial nerve terminals of the rat.
نویسندگان
چکیده
منابع مشابه
A slowly activating voltage-dependent K+ current in rat pituitary nerve terminals.
1. A novel slowly activating voltage-dependent K+ current was observed in isolated nerve terminals from rat neurohypophysis using the whole-cell configuration of the patch-clamp technique. 2. The activation kinetics of the slow current could be fitted assuming Hodgkin--Huxley-type kinetics, an exponential, n, of 1.3 and activation time constants decreasing from 4 s at -50 mV to 0.7s at +40 mV. ...
متن کاملDopamine D4 receptor mediated inhibition of potassium current in neurohypophysial nerve terminals.
Dopamine influences the release of neurohypophysial peptides in vivo. However, the extent to which this effect is caused by a direct dopaminergic action within the neurohypophysis remains unclear. With use of the patch-clamp technique on thin slices of rat posterior pituitary glands, we now provide evidence that dopaminergic agonists inhibit potassium current (IK) in neurohypophysial nerve term...
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We characterized the effects of the volatile anesthetic isoflurane on the ion currents that contribute to the action potential (AP) in isolated rat neurohypophysial (NHP) nerve terminals using patch-clamp electrophysiology. Mean resting membrane potential and AP amplitude were -62.3 +/- 4.1 and 69.2 +/- 2.9 mV, respectively, in NHP terminals. Two components of outward K(+) current (I(K)) were i...
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چکیده ندارد.
15 صفحه اولRole of Q-type Ca2+ channels in vasopressin secretion from neurohypophysial terminals of the rat.
1. The nerve endings of rat neurohypophyses were acutely dissociated and a combination of pharmacological, biophysical and biochemical techniques was used to determine which classes of Ca2+ channels on these central nervous system (CNS) terminals contribute functionally to arginine vasopressin (AVP) and oxytocin (OT) secretion. 2. Purified neurohypophysial plasma membranes not only had a single...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1991
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1991.sp018386